STUDY ON COAGULATION-FIBRINOLYSIS ACTIVITY IN OBSTRUCTIVE JAUNDICE

Obstructive Jaundice

Obstructive Jaundice

Introduction Neonatal cholestasis is defined as prolonged elevation of serum levels of conjugated bilirubin beyond the first 14 days of life. Neonatal hyperbilirubinaemia is usually physiologic, unconjugated, and self-limited. Only 2–15% of neonates remain jaundiced past 2 weeks of life, and just 0.2–0.4% have cholestatic jaundice from either intrahepatic cholestasis or structural abnormalities...

Endotoxaemia in Obstructive Jaundice

Surgical procedures in patients with obstructive jaundice are associated with significant morbidity and mortality1. This is due, to a large extent, to the development of postoperative complications such as sepsis, bleeding disorders and renal failure24. Clinical and experimental studies have suggested several aetiological factors for these complications including hypotension, impaired nutrition...

Postmenopausal hormone replacement therapy increases coagulation activity and fibrinolysis.

Hormone replacement therapy (HRT) appears to be cardioprotective in postmenopausal women; however, concerns exist over its thrombogenic effects. To address the effects of combined HRT on coagulation and fibrinolysis, we have measured circulating markers of these processes in a double-blind placebo-controlled trial. Forty-two healthy postmenopausal women aged 50 to 75 years received continuous c...

A Genetic Study of Neonatal Obstructive Jaundice.

Clarification of the problem of jaundice in the neonatal period began with the discovery of foetomaternal rhesus incompatibility as the usual cause of haemolytic disease of the newborn. After this, the group of infants in whom the jaundice is of obstructive type, with pale stools and bile in the urine, received more attention, and it was soon realized that not all such infants suffered from atr...